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16, 95 % CI 1.08-1.25). For the least exposed façade the HR for Ln 45 vs. ≤ 35 dB was 1.00, 95 % CI (0.95-1.05). For the most exposed façade, the overall association was strongest in smokers and physically inactive. CONCLUSION Long-term residential nighttime noise exposure at the most exposed façade may be associated with a higher likelihood of redeeming prescriptions for sleep medication, especially among men, smokers, and physically inactive. © Sleep Research Society 2020. Published by Oxford University Press on behalf of the Sl