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The aim of the present study is to investigate the effect of flavonoids from stem and leaf of Scutellaria baicalonsis Georgi (SSF) on multi-sites phosphorylation of tau protein in cerebral cortex and hippocampus of rats induced by okadaic acid (OA) and the regulative mechanism of the protein kinases. The model of AD-like memory impairment and neuronal injuries was established in male SD rats who were microinjected with OA (200 ng/kg) to establish a memory impairment model and screened for successful model rats by Morris water maze on day
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