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Untreated ADHD in Adults Can Lead to Feelings of Worthlessness and Depression Untreated ADHD can result in chronic underachievement and depression. This is especially relevant when they fail to achieve their personal and professional objectives. Diagnoses can be difficult to make when there are overlaps in symptoms between ADHD and depression. Identifying the symptoms is the first step to getting treatment. 1. Feelings of inadequateness Untreated ADHD and co-occ