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What is the Best Treatment For ADHD in Adults? The majority of people with ADHD will benefit from a combination treatment. These treatments are usually multimodal, including medication, therapy and lifestyle changes. The most frequently prescribed treatment for ADHD is stimulants. Finding the right dosage and balancing the side effects can be a trial and error process. Atomoxetine, an unstimulant FDA approved does not carry the abuse potential that can be associated wit