https://www.selleckchem.com/pr....oducts/ganetespib-st
Compared with the model group, GEG increased cell viability as well as proliferation (P0.05 or P0.01) and reduced β -gal expression. Furthermore, GEG significantly decreased the expressions of p16 , p53 and p21 proteins, and increased the expressions of CDK2, CDK4 and pRb proteins compared with the model group (P0.05 or P0.01). GEG can alleviate CTX-induced HSCs senescence in mice, and the p16 -Rb signaling pathway might be the underlying mechanism. GEG can alleviate CTX-induced HSCs senescence in mice, and t
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