https://www.selleckchem.com/pr....oducts/ro-20-1724.ht
" A statistically significant decrease over time is seen for cleft surgery and orthodontic treatment (P = 0.0017 and P = 0.0015, respectively). No statistically significant differences were found concerning the age at which treatment was received (P = 0.42). Significant associations between treatment modalities were found for orthognathic surgery and distraction osteogenesis (P less then 0.0001), orthognathic surgery and orthodontic treatment (P less then 0.0001), and between orthodontic treatment and distraction osteogenesis (P
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