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Injections are commonly used by health care practitioners to treat foot and ankle injuries in athletes despite ongoing questions regarding efficacy and safety. An extensive literature review was performed through MEDLINE, Google Scholar, and EBSCOhost from database inception to 2021. Keywords searched were , , , , , , and . Search results included articles written in the English language and encompassed reviews, case series, empirical studies, and basic science articles. Clinical review. Level 4. Corticosteroids, platelet-rich plasma/au