https://www.selleckchem.com/
Atopic dermatitis (AD) is characterized by a skin barrier defect aggravated by mechanical injury inflicted by scratching, a T 2 cell-dominated immune response, and susceptibility to viral skin infections that are normally restrained by a T 1 cell response. The signals leading to a T 2 cell-dominated immune response in AD are not completely understood. Our aim was to determine the role of IL-13 in initiation of the T cell response to cutaneously encountered antigens. Wild-type, Il13 , Il1rl1 , and Il4ra mice, as well as mice with selective deficiency of IL-1
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