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Untreated ADHD in Adults Can Lead to Feelings of Worthlessness and Depression People who are not treated for ADHD are often plagued by an inexplicably low level of performance, which can lead to feelings of worthlessness and depression. This is especially the case when they don't achieve their goals in terms of personal and professional. It are difficult to establish when there are commonalities in symptoms between ADHD and depression. Identifying the symptoms is the first step towards seeking treatment. 1. Feelings of Inadequacy Untreated ADHD and co-occurri