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0% and 3.3%, respectively. The adjusted odds of moderate to severe CP were lower in the MgSO4 group than in the placebo group (odds ratio 0.61; 95% confidence interval 0.23-1.65). CONCLUSIONS Antenatal MgSO4 before 32 weeks of gestation decreases the likelihood of moderate to severe CP, and these results are entirely consistent with other randomised evidence summarised in the linked trial sequential analysis. This article is protected by copyright. All rights reserved.Mycobacterium tuberculosis (Mtb) causes one of the most grievous pande