https://www.selleckchem.com/pr....oducts/eflornithine-
Furthermore, we found that HDAC inhibitors, trichostatin A or suberoylanilide hydroxamic acid infusion to hippocampus prevented the depressive behaviors induced by NAN-190, as well as histone H3 and H4 acetylation in mice. Our results suggested that epigenetic histone acetylation coupled with 5-HT1A receptor may play vital role in the pathophysiology and treatment of depressive disorders.Thiamine-dependent processes are critical in cerebral glucose metabolism, it is abnormity induces oxidative stress, inflamma
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