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1 vs 5.2years, P=.008). Survival rates and corresponding standard errors at 1, 2, 3, and 5years were 80±1% versus 82±0.7%, 70±1.5% versus 74±0.8%, 62±1.7% versus 66±0.9%, and 47±2.4% versus 52±1.3%, respectively. A survival difference was similarly observed for the subgroup analyses of moderate AS and reduced ejection fraction (P=.028) and moderate AS and low aortic valve gradients (P=.039). Moderate AS is associated with increased mortality. The increased mortality was also observed in the subgroups of patients with either reduced ejec