https://www.selleckchem.com/pr....oducts/pf-06650833.h
BACKGROUND Weakness affects motor performance and causes skeletal deformities in spinal muscular atrophy (SMA). Scoliosis surgery decision-making is based on curve progression, pulmonary function, and skeletal maturity. Benefits include quality of life, sitting balance, and endurance. Post-operative functional decline has not been formally assessed. OBJECTIVE To assess the impact of scoliosis surgery on motor function in SMA types 2 and 3. METHODS Prospective data were acquired during a multicenter natural history study. Seventeen p
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