https://www.selleckchem.com/pr....oducts/rottlerin.htm
BACKGROUND Isoindole-1,3(2H)-dione derivatives are known to have cytotoxic effects on many cancer cells. The anticancer activity of these compounds varies depending on the substituents attached to them. Therefore, the effect of substituents is very important when determining the anticancer activities of molecules. We have recently reported an example of the substituent effect. According to that work, the anticancer activity against HeLa, C6, and A549 cancer cell lines of isoindole-1,3(2H)-dione compounds containing tert-butyldiphenyls
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