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Severe vertebral osteoporosis is a rare condition in early postmenopausal women. We seek to determine whether Trabecular Bone Score (TBS), which is a new bone texture measurement, could be of additional value in evaluating trabecular bone properties in this population. Lumbar spine (LS) and femoral neck (FN) bone mineral densities (BMDs) and TBS were measured in 105 early postmenopausal women (group 1 "cases", mean age 53.1±2.6yrs.) with severe vertebral osteoporosis defined as a vertebral BMD T-score≤3, as well as in 105 healthy postm