https://www.selleckchem.com/pr....oducts/BAY-73-4506.h
In binary systems, it took less than 2 h to achieve equilibrium for each BFR at 60 °C, 25 MPa and 1000 rpm. In the presence of polymeric matrix, slower extraction kinetics were observed due to the occurrence of competitive dissolution and molecular diffusion within the matrix. Mathematical models derived from irreversible desorption and Fick's diffusion laws fitted well with the observed extraction kinetics of BFRs, thus enabling us to identify the rate-determining step. The high solubilization rate coefficients that we measured for
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