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Symptoms are exacerbated by moderate task, and exertional exhaustion is a vital complaint amongst sufferers. We modeled this exertional fatigue by having GWI (n = 8 and sedentary control (n = 31) subjects perform submaximal exercise stress tests on two successive days. Cognitive distinctions had been considered by evaluating fMRI scans carried out during 2-Back working memory tasks pre and post the exercise. Machine learning formulas were utilized to determine variations in mind activatio