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ADHD Treatment For Adults - Stimulant Medication Stimulant medicines like methylphenidate or dextroamphetamine are typically considered the as the first line treatment for adults with ADHD. These medications boost and balance levels of neurotransmitters, which are brain chemicals. Nonstimulant medications such as antidepressants and atomoxetine can be prescribed if stimulants aren't appropriate for the patient because of other health issues or adverse