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ADHD Treatment For Adults Stimulants such as methylphenidate, amphetamine, and other brain chemicals can help increase levels. Nonstimulants like atomoxetine or antidepressants are slower than stimulants, however, they can be just as beneficial. Complicating conditions often influence the response to ADHD medication. Physicians should address the most severe symptoms of any comorbid disorder first, then examine whether the ADHD symptoms improve. Medication Medication is the mo