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To report the results of a randomized controlled trial comparing outcomes between medium power (MP) and high power (HP) laser settings for HoLEPs. The primary objective was to compare the enucleation efficiency (EE) of HP- HoLEP (80-100W) with MP-HoLEP (50 - 60W). The secondary objectives were to compare treatment efficacy and safety between both groups. To show a 25% difference in EE, a sample size of 45 individuals per treatment arm was required (alpha = 0.05; Beta = 0.8. Patients demographic and perioperative factors were analyzed