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OBJECTIVE The objective of this study was to explore nurses' perspectives on diabetic foot ulcer's odor. METHOD A qualitative descriptive was the method of choice as a description of nurses' perspective on diabetic foot ulcer's odor. Data were collected using in-depth interviews with 19 nurses in the hospital and clinic setting in South Sulawesi, Indonesia, and analyzed using a thematic analysis. RESULTS Four major themes reported (1) indicator of DFU status, (2) discomfort with odor, (3) odors management and (4) therapeutic nurses' car