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Six samples gave inconclusive results, of which two had a fetal fraction of less then 4%. This study demonstrates that NIPD for SCD is approaching clinical utility. © 2020 British Society for Haematology and John Wiley Sons Ltd.Microglia have been known for decades as key immune cells that shape the central nervous system (CNS) during development and respond to brain pathogens and injury in adult life. Recent findings now suggest that these cells also play a highly complex role in several other functions of the CNS. In this review
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