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ADHD Treatment For Adults Stimulants like methylphenidate and amphetamine can boost the levels of certain brain chemicals. Nonstimulants, like atomoxetine and antidepressants, work slower than stimulants, but they can be beneficial too. Comorbid conditions can affect the response of ADHD medication. Physicians should treat the most severe symptoms of any co-occurring disorder first, and then examine whether the ADHD symptoms improve. Medication Medication is the most popular treatmen