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Delayed hemolytic transfusion reaction (DHTR) is a delayed effect, that occurs days to weeks after a transfusion, described as mild anemia and/or hyperbilirubinemia and it is one of the severe complications of bloodstream transfusion. The observable symptoms of DHTR resemble those of vaso-occlusive crisis secondary to SCD resulting in difficulty or delaying in diagnosis of DHTR. DHTR may lead to numerous organ failure and d
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