https://www.selleckchem.com/mTOR.html
The PCa patients Gleason score and tumor node metastasis (TNM) positively correlated with promoter methylation level of serum DACT-2. The DACT-2 methylation rate was 0.745 with a sensitivity of 81.8%, and a specificity of 75.0%, the sensitivity, and specificity of PSA was 80.1% and 59.4%. ROC curve results displayed that the diagnostic value of DACT-2 is superior to PSA. Our study confirms that the level of methylation of the DACT-2 promoter in patients with PCa is much higher than that in patients with benign prostatic hyperplasia (BPH) and health
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