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y be a fundamental mechanism that drives functional decline of adipose tissues during obesity. Our data demonstrate that adipocytes fail to maintain cellular identity after HFD feeding, acquiring characteristics of a myofibroblast-like cell type through reduced PPARγ activity and elevated TGFβ-SMAD signaling. This cellular identity crisis may be a fundamental mechanism that drives functional decline of adipose tissues during obesity. Segment coordination variability (CV) is a movement pattern associated with running-related injuries. It