https://www.selleckchem.com/pr....oducts/Novobiocin-so
In this paper a nonlinear least-squares method is used. In addition to the derivation of this technique, the method is validated in two scenarios and the results are compared to those obtained by the general purpose optimal control software, GPOPS-II. In general, the proposed technique produces solutions of O ( 10 - 10 ) accuracy. Additionally, for the proposed test cases, it is reported that each individual TFC-based inner-loop iteration converges within 6 iterations, each iteration exhibiting a computational time
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