https://www.selleckchem.com/pr....oducts/kd025-(slx-21
Organ-at-risk sparing was improved with PBT versus IMRT; mean heart 2.0 versus 7.4 Gy (P .01), V30 Gy heart 2.6% versus 10.7% (P .01), mean lung 7.9 versus 10.4 Gy (P=.042), V5 Gy lung 23.4% versus 42.1% (P .01), and V10 Gy lung 20.4% versus 29.6% (P .01). TTB was reduced with PBT (OR, 0.35; 95% CI, 0.15-0.83; P=.017). Rates of cardiac toxicity were 14.7% IMRT and 4.9% PBT (P=.09). Rates of ≥ grade 2 pneumonitis were 17.0% IMRT and 4.9% PBT (P=.104). PBT improved cardiac and lung sparing and reduced toxicity
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