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PDX tumors supply a proxy for the development regarding the patient cyst by re-grafting them through several passages to immune-compromised mice. The HLA peptidomes of personal biopsies were in comparison to those derived from PDX tumors. Bigger HLA peptidomes were obtained from the somewhat larger PDX tumors as compared to the individual biopsies. The HLA peptidomes of different PDX tumors derived from the exact same origin tumor biopsy had been extremely reproducible, also after subsequent passages to brand-new
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