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https://dup753antagonist.com/s....exual-dysfunction-pu
Base editing gets the potential to directly fix point mutations and offer healing renovation of gene purpose. Mutations of transmembrane channel-like 1 gene (TMC1) may cause prominent or recessive deafness. We created a base modifying strategy to treat Baringo mice, which carry a recessive, loss-of-function point mutation (c.A545G; causing the substitution p.Y182C) in Tmc1 which causes deafness. Tmc1 encodes a protein that forms mechanosensitive ion networks in physical hair cells of this inner e