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HBV VLs correlated well between both assays, across all genotypes (Pearson correlation coefficient r = 0.987). Six samples exceeded a 0.5 log difference between assays. Bland-Altman analysis demonstrated a mean of the difference of -0.107 log and a standard deviation of 0.271 log. High correlation was observed between the Roche Cobas HBV Viral Load tests and the Xpert HBV Viral Load Assay, thus enabling rapid, random access, and accurate HBV VL assessment. High correlation was observed between the Roche Cobas HBV Viral Load tests and t