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26 (2.25, 2.31) mmol/L vs 1.90 (1.87, 1.97) mmol/L, respectively (p less then 0.001). Both UA and LA levels decreased significantly after CPAP treatment [median (IQR) 7.0 (6.4, 8.1) mg/dL vs 6.4 (6.2, 6.8) mg/dL, p less then 0.001 and 2.26 (2.25, 2.31) mmol/L vs 2.08 (2.07, 2.31) mmol/L, p less then 0.001]. Several sleep parameters were independent predictors of UA and LA levels.Conclusion In OSAS patients increased serum UA and arterial LA levels are found. CPAP therapy resulted in significant reductions in levels of both biomarkers.Introd