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Discussion Factors influencing participation may be leveraged to improve recruitment and retention within observational and therapeutic studies requiring serial LPs. © 2020 The Authors. Alzheimer's Dementia Diagnosis, Assessment Disease Monitoring published by Wiley Periodicals, Inc. on behalf of the Alzheimer's Association.Introduction Apolipoprotein E ε4 (APOE4)-related genetic risk for sporadic Alzheimer's disease is associated with an early impairment of cognitive brain networks. The current study determines relationships
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