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hat CCL3, CCL4, CCL9 and their receptors offer promising targets for influencing secondary neuronal injury and improving TBI therapy. The results suggest that the MIP-1 family is an important target for pharmacological intervention for brain injury. AIM To collate and synthesise current research evidence related to interventions that support safe medication administration by nurses in emergency departments (ED). INTRODUCTION Medications are associated with a higher incidence of adverse events than other healthcare interventions and they