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Along with past reports, the outcomes indicate that MT-TN is a hot place for mutations causing sporadic PEO.We explain two MT-TN mutations associated with PEO and mitochondrial myopathy, and their pathogenicity had been demonstrated. As well as past reports, the outcomes suggest that MT-TN is a hot area for mutations causing sporadic PEO. This study includes a sample of 461 juvenile individuals (6 months to 15 years of age) who underwent evaluation at the University of th