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Chemotherapy, Individualized management, Infection control management mode under medical care integration/Nursing, Peripherally inserted central catheter (PICC). Chemotherapy, Individualized management, Infection control management mode under medical care integration/Nursing, Peripherally inserted central catheter (PICC).Aging impairs mitochondrial function that leads to greater cardiac injury during ischemia and reperfusion. Cardiac endoplasm reticulum (ER) stress increases with age and contributes to mitochondrial dysfunction. Metfor