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HA chain preserves a rigid rod-like conformation with quick sequence lengths. Crossover from a rod-like to a random-coil conformation is seen with enhancing the string length. The conformation with the β(1,4) linkage is more versatile than that with the β(1,3) linkage. Variation of this radius of gyration and conformational fluctuation revealed that the β(1,4) linkers combined with the HA chain length improve the overall conformational flexibility and as a consequence flexible response of the polymer chain. Besides the i