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This work provides a proof of concept for the design of ultra-high-affinity binders of target proteins through dimerized nanobody chimaeras, and this strategy may also be applied to link interesting target protein nanobodies without overlapping binding surfaces.Life cycle-based analyses are considered crucial for designing product value chains towards lower carbon emissions. We have used data reported by companies to CDP for public disclosure to build a database of 866 product carbon footprints (PCFs), from 145 companies, 30 industries,