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https://www.selleckchem.com/pr....oducts/sbi-0206965.h
All participants maintained a VL 40 copies/ml, while ER-niacin did not affect CD4 and CD8 cell counts. Plasma levels of triglycerides, total, and LDL cholesterol significantly decreased, following ER-niacin treatment. ER-niacin also diminished Kyn plasma levels and slightly decreased CD4 T-cell activation. However, no improvement in CD8 subsets, Kyn/Trp ratio, Th17/Treg balance, and plasma inflammatory markers was observed. Although ER-niacin combined with ART was well-tolerated among immune non-responders and decreased plasma