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d after anterior cruciate ligament reconstruction, which is associated with poorer quadriceps strength and knee function. The effect of modulation of muscle stiffness on improving knee function warrants future investigation.Silica xerogels were prepared by the sol-gel method under ultrasonic irradiation, using tetraethylorthosilicate (TEOS) as the starting material. Hexamethyldisiloxane (HMDSO) was used as the hydrophobizing agent. When preparing silica xerogel, it is necessary to perform aging and hydrophobization to suppress shrinkage during ambient press