https://www.selleckchem.com/pr....oducts/tauroursodeox
Moreover, pancreatic deletion of IL-1α led to impaired glucose tolerance with no change in insulin sensitivity. This observation was consistent with our finding that glucose-stimulated insulin secretion was reduced in islets isolated from IL-1α mice. Alternatively, IL-1α mice (male and female) did not have any detectable changes in glucose tolerance, respiratory quotient, physical activity, or food intake when compared with littermate controls. Taken together, we conclude that there is an important physiological role f
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