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≤ -0.4), with the following pattern (worse to better) GnRH agonist GnRH antagonist no gonadotropin stimulation. Conclusions This is the first systematic review exploring the psychopathological effects of hormonal infertility treatments. Our study suggests that protocols without gonadotropin stimulation show a better mood profile when compared to those using GnRH antagonists or GnRH agonists. Future studies need to include patients with major mood and psychotic disorders.Background The nine-item Internet Gaming Disorder Scale-Sho