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Increased 1,25-D amount also led to concurrent rapid and remarkable depletion of circulatory 25-D. Conclusions In conclusion, extrarenal 1,25-D could access the systemic blood circulation and as a consequence, may have systemic impacts besides its autocrin and paracrine features.Background Using the analysis of focal epi-cardial coronary stenosis and non-obstructive atherosclerosis, the cardiac scans play significant part in diagnosing coronary artery