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ADHD Treatment For Adults The stimulants like methylphenidate amphetamine, and other brain chemicals can help increase levels. Nonstimulants like atomoxetine or antidepressants are slower than stimulants, however, they can be just as helpful. Complicating conditions often influence the response to ADHD medications. The most severe symptoms from any comorbid condition must be treated first. Then, the doctor should monitor whether ADHD symptoms improve. Me