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This article is shielded by copyright. All rights set aside.Recently, minicircle (MC)-based cellular therapy is appearing as a novel technology for non-viral hereditary customization. In this study, we investigated the faculties of granulocyte chemotactic protein-2 (GCP-2)-overexpressing fibroblasts (GCP-2/MC) utilizing MC microporation technology, in addition to its therapeutic mechanism in wound healing. GCP-2 moms and dad plasmid and MC containing GCP-2 had been created. Human d