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Whether different patterns of recurrence reflect biological heterogeneity requires further investigation. Surgical resection offers the chance for prolonged survival and even for cure in recurrent cholangiocarcinoma. Hence, it is of the utmost importance to better understand the routes of metastases and to define factors qualifying for resection. Whether different patterns of recurrence reflect biological heterogeneity requires further investigation. Prevention of posthepatectomy liver failure is a prerequisite for improving the postopera
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