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https://ml198activator.com/sin....gle-burr-hole-length
We leverage this to train a straightforward and simply interpretable predictive model that outperforms various other present predictors and permits us to classify 1,760 genes-which tend to be currently unascertained in gnomAD-as highly LoF intolerant or not. These predictions possess prospective to assist in the explanation of book variants when you look at the clinical setting. Moreover, our outcomes reveal that high CpG thickness is certainly not merely a generic funct