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https://www.selleckchem.com/pr....oducts/pf-07265807.h
There were no differences in serum estradiol concentration (p=0.929) and duration of therapy (p=0.496) between formulations. Transgender women demonstrated hypercoagulable parameters on both thromboelastography (maximum amplitude +6.94mm (3.55, 10.33), p less then 0.001) and thrombin generation (endogenous thrombin potential +192.62nM.min (38.33, 326.91), p=0.009; peak thrombin +38.10nM (2.27, 73.94), p=0.034) but had increased overall fibrinolytic potential (+4.89% (0.52, 9.25), p=0.024) compared to cisgender men. No significant ch