https://www.selleckchem.com/pr....oducts/Sunitinib-Mal
F8 int1h inversions (Inv1) are detected in 1%-2% of severe hemophilia A (HA) patients. Long-range polymerase chain reaction (PCR) and inverse-shifting PCR have been used to diagnose these inversions. To design and validate a sensitive and robust assay for detection of F8 Inv1 inversions. Archival DNA samples were investigated using mile-post assays and droplet digital PCR. Milepost assays for Inv1 showing high specificities and sensitivities were designed and optimized. Analysis of four patients, two carrier mothers, a
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