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A ROC curve determined the optimal synovial white blood cell cutoff for diagnosing septic arthritis in native joints for each group. The ROC curve determined that patients who received antibiotics had an optimal cutoff of 16,000 cells (sensitivity = 82%, specificity = 76%), and a neutrophil percentage cutoff of 90% (sensitivity = 73%, specificity = 74%). The control group had an optimal synovial leukocyte cutoff of 33,000 cells (sensitivity = 96%, specificity = 95%). The optimal neutrophil percentage cutoff in the control grou